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. Author manuscript; available in PMC: 2015 Oct 7.
Published in final edited form as: Chem Soc Rev. 2015 Jun 9;44(17):6258–6286. doi: 10.1039/c4cs00511b

Figure 8.

Figure 8

Multi-modal nanotheranostics of CTCs in the blood circulation system with multifunctional targeting nanomedicines. Multiple antibodies as listed in Table 2 can be selected to co-conjugate on the nanomedicine to enhance the accuracy of individualized CTC detection. Multifunctional nanoparticle platforms, especially rattle-structured ones, can be used to realize in vivo theranostic of CTCs by combining a variety of diagnosis and therapy modes, such as photothermal/magnetothermal/radiosensitizing/chemical/photodynamic/HIFU therapies and MRI/fluorescent/photoacoustic/CT diagnoses.