Table 1.
Subject Characteristics at enrollment for FHN Patients with available data for non-linear HRV Indices. Results are shown as mean ± standard deviation or frequency (%), as appropriate.
| Variables | All (N=210) | Diabetic (N=85) | Non-diabetic (N=118) | |||
|---|---|---|---|---|---|---|
|
| ||||||
| N | N | N | ||||
|
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| Age (years) | 210 | 49.8 ± 13.5 | 85 | 55.4 ± 12.3§ | 118 | 45.8 ± 13.1 |
|
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| Male | 210 | 130 (62%) | 85 | 50 (59%) | 118 | 76 (64%) |
|
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| Diabetes | 203 | 85 (42%) | -- | 73 (41%) | 27 | 12 (44%) |
|
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| Pre-dialysis albumin (per 0.1 g/dL) | 206 | 39.3 ± 4.0 | 85 | 38.3 ± 3.6* | 117 | 40.1 ± 4.0 |
|
| ||||||
| Pre-dialysis phosphorus (mg/dL) | 206 | . | 85 | . | 117 | . |
| <5.5 | 98 (48%) | 39 (46%) | 56 (48%) | |||
| >=5.5 and <7.0 | 65 (32%) | 27 (32%) | 37 (32%) | |||
| >=7.0 | 43 (21%) | 19 (22%) | 24 (21%) | |||
|
| ||||||
| Hemoglobin (g/dL) | 198 | 11.9 ± 1.3 | 82 | 11.8 ± 1.3 | 112 | 12.0 ± 1.4 |
|
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| Residual Renal Clearance (L) | . | . | . | |||
| 0 | 127 (62%) | 50 (59%) | 77 (66%) | |||
| >0 and <=0.8 | 204 | 22 (11%) | 85 | 10 (12%) | 117 | 12 (10%) |
| >0.8 and <1.4 | 20 (10%) | 9 (11%) | 11 (9%) | |||
| >1.4 | 35 (17%) | 16 (19%) | 17 (15%) | |||
|
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| Weekly enPCR (g/kg/d) | 204 | 10.6 ± 2.8 | 85 | 10.8 ± 2.9 | 117 | 10.4 ± 2.7 |
|
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| eKt/V | 204 | 1.42 ± 0.25 | 85 | 1.40 ± 0.26 | 117 | 1.45 ± 0.24 |
|
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| Left Ventricular Mass (g) | 177 | 146 ± 59 | 74 | 142 ± 49 | 103 | 149 ± 64 |
|
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| Left Ventricular End-diastolic Vol. (ml) | 177 | 182 ± 64 | 74 | 174 ± 52 | 103 | 188 ± 71 |
|
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| Left Ventricular Ejection Fraction (%) | 177 | 56.7 ± 11.2 | 74 | 54.5 ± 13.0# | 103 | 58.3 ± 9.6 |
|
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| Heart Rate as Measured Centrally (bpm) | 177 | 75.9 ± 13.9 | 74 | 75.9 ± 12.6 | 103 | 75.9 ± 14.8 |
|
| ||||||
| Urine Volume (L) | 210 | . | 85 | . | 118 | . |
| 0 | 151 (72%) | 58 (68%) | 86 (73%) | |||
| >0 and <=1 | 57 (27%) | 27 (32%) | 30 (25%) | |||
| >1.0 | 2 (1%) | 0 | 2 (2%) | |||
|
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| Extra-cellular Volume (L) | 193 | 22.9 ± 4.7 | 80 | 24.5 ± 4.7* | 112 | 21.9 ± 4.4 |
|
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| Extra-cellular Volume/Total Volume | 193 | 0.523 ± 0.067 | 80 | 0.536 ± 0.068# | 112 | 0.513 ± 0.065 |
|
| ||||||
| Lean Body Mass | 193 | 44.6 ± 10.3 | 80 | 46.3 ± 10.3 | 112 | 43.5 ± 10.1 |
|
| ||||||
| Ultrafiltration volume (L) | 206 | 3.33 ± 1.20 | 85 | 3.60 ± 1.23# | 117 | 3.17 ± 1.16 |
|
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| Physical Health Composite (RAND SF36) | 203 | 37.4 ± 10.9 | 83 | 34.4 ± 10.6* | 115 | 39.6 ± 10.7 |
|
| ||||||
| Physical Functioning Scale (SF36) | 204 | 55.9 ± 27.4 | 84 | 44.8 ± 26.6§ | 115 | 63.6 ± 25.4 |
|
| ||||||
| Short Physical Performance Battery Score | 206 | 10.9 ± 3.0 | 85 | 9.92 ± 3.08§ | 117 | 11.6 ± 2.8 |
Significant differences between diabetic and non-diabetic groups are shown in bold font:
§
p-value≤0.0001,
*
p-value<0.005,
#
p-value<0.05