Figure 1.
Oral administration of D156844 augmented the follistatin-induced increase in survival of SMNΔ7 SMA mice. Kaplan-Meier survival plot for SMNΔ7 SMA mice receiving either vehicle (light gray dotted line; n = 17), 1 mg/kg/qad follistatin (gray dashed line; n = 20) or a combination of 3 mg/kg/d D156844 and 1 mg/kg/qad follistatin (solid line; n = 23). Treatment of SMNΔ7 SMA mice began at PND04.