Table III.

Effect of TBI on Liver Metabolizing Enzymes. Genes differentially expressed (>1.5-fold change, p < 0.05)

Affymetrix ID	Symbol	Genes	$\frac{\mathrm{Vehicle}+\mathrm{T}\mathrm{B}\mathrm{I}}{\mathrm{Sham}}$ a
24 h post-TBI
10716509	Ces2c	Carboxylesterase 2C	1.78
10871087	Cyp4a1	Cytochrome P450, family 4, subfamily a, polypeptide 1	1.63
10878780	Cyp4a2	Cytochrome P450, family 4, subfamily a, polypeptide 2	1.60
10878767	Cyp4a8	Cytochrome P450, family 4, subfamily a, polypeptide 8	1.65
10914411	Cyp8b1	Cytochrome P450, family 8, subfamily b, polypeptide 1	1.50
10853471	Cyp51	Cytochrome P450, family 51	1.59
10811341	Hsd17b2	Hydroxysteroid (17-beta) dehydrogenase 2	1.78
10769680	Hsd17b7	Hydroxysteroid (17-beta) dehydrogenase 7	1.88
10810867	Nqo1	NAD(P)H dehydrogenase, quinone 1	1.78
10868726	Aldh1b1	Aldehyde dehydrogenase 1 family, member B1	0.63
10807083	Ces2g	Carboxylesterase 2G	0.56
10770342	Ephx1	Epoxide hydrolase 1, microsomal	0.63
10918822	Gsta2	Glutathione S-transferase A2	0.66
10863686	Nat8	N-Acetyltransferase 8	0.52
10771978	Ugt2b7	UDP glucuronosyltransferase 2 family, polypeptide B7	0.66
72 h post-TBI
10863686	Nat8	N-Acetyltransferase 8	0.65
10875324	Cyp7a1	Cytochrome P450, family 7, subfamily a, polypeptide 1	1.94
10811341	Hsd17b2	Hydroxysteroid (17-beta) dehydrogenase 2	1.74
7 days post-TBI
10719187	Sult2a1	Sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1	1.51

^aFold change in gene expression