Fig. 2.

In vivo anti-tumor activity of HGC, Cremophor EL-based PTX, and PTX-HGC nanoaggregates after administration i.v. Arrows indicate the times of injection The results represent the means ± SD (n = 6). The symbols are as follows: saline (black circle); HGC (black square); Cremophor EL-based PTX, equivalent to 20 mg/kg PTX (black triangle); PTX-HGC, equivalent to 20 mg/kg PTX (black inverted triangle); and PTX-HGC, equivalent to 50 mg/kg PTX (black diamond). Reprinted with permission from (14). Copyright © 2006 Elsevier