Fig. 3.

Effect of α-spinasterol on the seizure threshold in the 6 Hz seizure test. α-Spinasterol was administered i.p. 30 min prior to the test. The doses are shown on the abscissa. Control animals received 1 % DMSO. Data are presented as CS₅₀ (in mA) values with upper 95 % confidence limits. Each CS₅₀ value represents current intensity predicted to produce convulsions in 50 % of mice. ***p < 0.001 vs. the control group (one-way ANOVA followed by Dunnett’s post hoc test)