Table 4.
Cognitive performance and psychopathological manifestation with respect to the IL6-174G/C polymorphism
| the IL6 -174G/C genotype | p valuea | |||
|---|---|---|---|---|
| CC (n = 39) | GC (n = 72) | GG (n = 40) | ||
| PANSS—positive symptoms | 17, 17.99 (6.23) | 18, 19.74 (7.72) | 23, 21.76 (5.95) | 0.24 |
| PANSS—negative symptoms | 24, 23.09 (7.57) | 21, 21.89 (8.52) | 24, 25.28 (7.85) | 0.28 |
| PANSS—general symptoms | 39, 39.74 (7.89) | 38, 39.79 (11.28) | 43, 43.64 (11.66) | 0.53 |
| PANSS—total score | 82, 80.78 (17.68) | 75, 81.42 (24.96) | 87, 90.22 (23.65) | 0.36 |
| PANSS—depression item | 1, 1.77 (1.10) | 1, 1.72 (1.01) | 1, 1.70 (1.17) | 0.97 |
| SAPS | 26, 19.71 (15.93) | 25, 31.32 (21,47) | 37, 38.48 (20.37) | 0.11 |
| SANS | 37, 41.39 (19.44) | 31, 36.53 (21.39) | 45, 47.64 (21.11) | 0.12 |
| TMT, part A | 45, 48.80 (27.5) | 41, 50.46 (48.3) | 42, 39.98 (29.0) | 0.98 |
| TMT, part B | 109, 136.58 (99.0) | 101, 140.17 (113.7) | 110, 101.73 (79.3) | 0.95 |
| Stroop, congruent | 37, 40.71 (12.9) | 40, 37.08 (22.0) | 41, 40.53 (17.7) | 0.49 |
| Stroop, incongruent | 81.50, 87.75 (35.8) | 72, 80.04 (35.6) | 75, 81.33 (39.7) | 0.70 |
| RAVLT, first immediate recall | 4, 3.25 (1.93) | 4.50, 4.35 (1.87) | 4, 4.55 (2.38) | 0.79 |
| RAVLT, second immediate recall | 6, 6.39 (2.59) | 7, 6.32 (2.45) | 6, 7.39 (2.62) | 0.78 |
| RAVLT, third immediate recall | 8, 7.39 (2.62) | 7, 7.14 (2.43) | 8, 7.27 (2.98) | 0.88 |
| RAVLT, fourth immediate recall | 9, 8.30 (2.98) | 8, 8.43 (2.63) | 9, 8.95 (3,03) | 0.93 |
| RAVLT, fifth immediate recall | 9, 8.78 (3.60) | 9, 8,84 (2.30) | 9, 9.45 (3.00) | 0.70 |
| RAVLT, inference | 8, 7.32 (3,03) | 7, 7.43 (2.91) | 7, 7.60 (2.99) | 0.96 |
| RAVLT, delayed recall | 7, 6.00 (3.49) | 6.5, 6.65 (2.44) | 6, 6.84 (3.10) | 0.74 |
| RAVLT, recognition | 11, 9.41 (4.68) | 10, 9.90 (3.48) | 10, 9.24 (3.60) | 0.48b |
| Verbal fluency, F words | 5, 5.91(3.76) | 7, 7.22 (3.70) | 6, 5.4 3 (4.16) | 0.29 |
| Verbal fluency, A words | 5, 6.13 (3.47) | 6, 7.35 (3.85) | 6, 5.41 (3.30) | 0.11 |
| Verbal fluency, S words | 8, 8.52 (4.71) | 9, 8.19 (3.25) | 7, 7.91 (3.38) | 0.38 |
| Verbal fluency, K words | 10, 10.43 (4.94) | 12, 12.32 (4.61) | 10, 10.59 (4.23) | 0.18 |
| Verbal fluency, supermarket | 16, 17.52 (7.98) | 15, 15.70 (5.85) | 13, 15.14 (7.19) | 0.35 |
| Forward digit span | 6, 6.14 (1.78) | 6, 6,20 (1.96) | 6, 6.08 (1.89) | 0.90 |
| Backward digit span | 5, 5.23 (2.47) | 5, 5.23 (2.04) | 5, 5.04 (2.30) | 0.99 |
| Digit symbols coding | 37.50, 40.73 (15.81) | 34, 35.78 (12.49) | 37, 36.88 (14.59) | 0.37 |
| Similarities | 14, 14.39 (5.33) | 14, 16.00 (5.41) | 15, 16.55 (3.76) | 0.47 |
n number of patients
Median, mean and standard deviation values are presented
aANOVA test, b Kruskal–Wallis test