Table 5.
Correlations between clinical, demographic and cognitive correlates with plasma hsCRP and IL-6 levels in schizophrenia patients
| Clinical correlates | hsCRP | IL-6 |
|---|---|---|
| Psychopathology | ||
| PANSS—positive symptoms subscale | r = −0.14, p = 0.20 | r = −0.05, p = 0.66 |
| PANSS—negative symptoms subscale | r = 0.01, p = 0.94 | r = 0.15, p = 0.23 |
| PANSS—general symptoms subscale | r = −0.12, p = 0.28 | r = −0.04, p = 0.73 |
| PANSS—depression item score | r = −0.06, p = 0.60 | r = 0.19, p = 0.10 |
| SAPS | r = −0.03, p = 0.78 | r = −0.05, p = 0.66 |
| SANS | r = −0.05, p = 0.67 | r = 0.15, p = 0.22 |
| Cognitive tasks | ||
| TMT, part A | r = 0.09, p = 0.39 | r = 0.38, p = 0.001* |
| TMT, part B | r = 0.19, p = 0.09 | r = 0.48, p = 0.001* |
| TMT, part A- TMT, part B | r = 0.19, p = 0.09 | r = 0.34, p = 0.005 |
| Stroop, congruent | r = 0.06, p = 0.58 | r = 0.27, p = 0.024 |
| Stroop, incongruent | r = 0.17, p = 0.13 | r = 0.34, p = 0.005 |
| RAVLT, first immediate recall | r = −0.38, p < 0.001* | r = −0.37, p = 0.002 |
| RAVLT, second immediate recall | r = −0.33, p < 0.001* | r = −0.31, p = 0.009 |
| RAVLT, third immediate recall | r = −0.32, p = 0.003 | r = −0.40, p = 0.001* |
| RAVLT, fourth immediate recall | r = −0.34, p = 0.002 | r = −0.39, p = 0.001* |
| RAVLT, fifth immediate recall | r = −0.29, p = 0.007 | r = −0.37, p = 0.001* |
| RAVLT, inference | r = −0.15, p = 0.170 | r = −0.25, p = 0.037 |
| RAVLT, delayed recall | r = −0.23, p = 0.049 | r = −0.28, p = 0.024 |
| RAVLT, recognition | r = −0.33, p = 0.004 | r = −0.36, p = 0.003 |
| Verbal fluency, F words | r = 0.16, p = 0.162 | r = −0.23, p = 0.059 |
| Verbal fluency, A words | r = −0.01, p = 0.927 | r = −0.29, p = 0.014 |
| Verbal fluency, S words | r = 0.16, p = 0.163 | r = −0.17, p = 0.156 |
| Verbal fluency, FAS total score | r = 0.11, p = 0.329 | r = −0.31, p = 0.011 |
| Verbal fluency, K words | r = 0.07, p = 0.550 | r = −0.22, p = 0.087 |
| Verbal fluency, supermarket | r = 0.11, p = 0.343 | r = 0.13 p = 0.289 |
| Forward digit span | r = −0.01, p = 0.920 | r = −0.27, p = 0.026 |
| Backward digit span | r = −0.04, p = 0.730 | r = −0.17, p = 0.164 |
| Digit symbol coding | r = −0.19, p = 0.098 | r = −0.45, p < 0.001* |
| Similarities | r = −0.02, p = 0.842 | r = 0.48, p = 0.149 |
| Demographic and clinical correlates | ||
| Age | r = 0.11, p = 0.31 | r = 0.26, p = 0.220 |
| BMI | r = 0.12, p = 0.505 | r = 0.26, p = 0.062 |
| Pack-year index | r = 0.05, p = 0.781 | r = 0.09, p = 0.523 |
| Chlorpromazine equivalent | r = 0.32, p = 0.009 | r = 0.57, p < 0.001* |
| Illness duration | r = 0.19, p = 0.073 | r = 0.30, p = 0.008 |
Significant associations were marked in bold characters (p value <0.05, 2-tailed)
* Significant correlations after the application of Bonferroni correction (p < 0.00147)