Table 3.
Drinking patterns and risk of total cancer
| Women | Men | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Cases (no) | Person years (no) | Multivariable RR (95% CI)* | Multivariable RR (95% CI)† | Cases (no) | Person years (no) | Multivariable RR (95% CI)* | Multivariable RR (95% CI)† | ||
| Frequency of drinking (drinks/week) | |||||||||
| 0 | 5166 | 512 091 | 1 (ref) | 1 (ref) | 1633 | 187 897 | 1 (ref) | 1 (ref) | |
| 1-2 | 3069 | 326 224 | 1.00 (0.96 to 1.05) | 0.98 (0.93 to 1.03) | 1499 | 187 663 | 1.02 (0.95 to 1.10) | 0.99 (0.90 to 1.08) | |
| 3-4 | 1236 | 119 744 | 1.03 (0.97 to 1.10) | 1.00 (0.93 to 1.07) | 727 | 90 762 | 1.00 (0.92 to 1.10) | 0.95 (0.85 to 1.07) | |
| 5-6 | 1385 | 112 878 | 1.09 (1.03 to 1.17) | 1.02 (0.94 to 1.10) | 826 | 92 965 | 1.01 (0.93 to 1.11) | 0.94 (0.84 to 1.07) | |
| 7 | 986 | 81 299 | 1.08 (1.01 to 1.16) | 0.97 (0.88 to 1.06) | 957 | 84 137 | 1.09 (1.00 to 1.19) | 0.99 (0.87 to 1.12) | |
| Ptrend‡ | — | — | <0.001 | 0.98 | — | — | 0.10 | 0.72 | |
| Highest no of drinks consumed in 1 day | |||||||||
| 0 | 4881 | 453 421 | 1 (ref) | 1 (ref) | 1403 | 149 861 | 1 (ref) | 1 (ref) | |
| 1-2 | 5969 | 570 288 | 1.04 (1.00 to 1.08) | 1.02 (0.97 to 1.07) | 2206 | 231 914 | 1.02 (0.95 to 1.09) | 0.98 (0.90 to 1.07) | |
| 3-5 | 2040 | 207 471 | 1.06 (1.00 to 1.12) | 0.99 (0.93 to 1.06) | 903 | 103 447 | 1.05 (0.96 to 1.15) | 0.97 (0.87 to 1.09) | |
| ≥6 | 498 | 44 084 | 1.13 (1.03 to 1.24) | 1.05 (0.95 to 1.17) | 224 | 24 735 | 1.13 (0.98 to 1.31) | 1.03 (0.87 to 1.22) | |
| Ptrend§ | — | — | <0.001 | 0.18 | — | — | 0.16 | 0.96 | |
RR=relative risk; ref=reference.
*Adjusted for the same covariates as listed in table 2.
†Adjusted for total alcohol intake.
‡Calculated using continuous days of alcohol consumption.
§Calculated using the median of each category as a continuous variable.