Neuromuscular synaptic activity is normal in UbG76V-GFP transgenic mice. A, Sample traces of mEPPs recorded from the lumbrical muscles from control and UbG76V-GFP mice (8 months of age). B, Quantification of mEPP frequencies (UbG76V-GFP mice: 1.39 ± 0.05 Hz, n = 13; control mice: 1.36 ± 0.05 Hz, n = 15). No significant difference is found between UbG76V-GFP and control mice. C, EPPs recorded from the lumbrical muscles from UbG76V-GFP and control mice (8 months of age). D, Quantification of EPP amplitudes. EPP amplitudes are similar between UbG76V-GFP mice (25.82 ± 0.80 mV, n = 13 muscle fibers, N = 3 mice) and control mice (26.76 ± 0.61 mV, n = 15 muscle fibers, N = 3 mice). E, EPPs recorded from the lumbrical muscles in UbG76V-GFP and control mice (8 months of age) in response to a 1 s, 100 Hz train stimulation (only the first 20 EPPs are displayed). Similar responses are detected from UbG76V-GFP and from control mice.