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. 2015 Jul 22;27(7):2365–2371. doi: 10.1589/jpts.27.2365

Table 2. Effects of exercise intervention on the inflammatory factors in diabetes patients.

Items CT group (n = 20) IT group (n = 22) Control group (n = 20)


Pre-treatment Post-treatment Pre-treatment Post-treatment
TLR4 mRNA 1.68 ± 0.29** 0.77 ± 0.18 1.85 ± 0.31** 0.54 ± 0.63**Δ 1.05 ± 0.18
NF-κBp65mRNA 1.28 ± 0.26** 1.01 ± 0.11 1.41 ± 1.77** 0.86 ± 0.66Δ 0.86 ± 0.12
TLR4 protein 0.95 ± 0.34** 0.67 ± 0.33* 0.86 ± 0.25** 0.41 ± 0.16Δ 0. 45 ± 0.17
NF-κBp65 protein 0.88 ± 0.36** 0.64 ± 0.25* 0.85 ± 0.24** 0.49 ± 0.21ΔΔ 0.45 ± 0.21
YKL40 0.41 ± 0.11 0.34 ± 0.21 0.31 ± 0.14 0. 28 ± 0.09 0.27 ± 0.11
IL-18 0.80 ± 0.12** 0.72 ± 0.12* 0.81 ± 0.09** 0.51 ± 0.10Δ 0.59 ± 0.31
PTX3 0.63 ± 0.13 0.63 ± 0.14 0.64 ± 0.15 0.58 ± 0.08 0.54 ± 0.78
IL-33 0.40 ± 0.09** 0.65 ± 0.12* 0.42 ± 0.14** 0.85 ± 0.14*ΔΔ 1.38 ± 0.19

Data are mean ± SD, *p < 0.05, **p < 0.01 vs. control group; Δp < 0.05, ΔΔp < 0.01 vs. conventional therapy group. CT group: the conventional therapy group; IT group: the intensive therapy group; IL-18: interleukin-18; IL-33: interleukin-33; NF-κBp65: Nuclear factor-κBp65; PTX3: pentraxin-related protein 3; TLR4: Toll-like receptor 4; YKL40: human cartilage glycoprotein 39