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. 2015 Aug 18;53(9):3032–3034. doi: 10.1128/JCM.01691-15

TABLE 1.

Resolution of discordant rifampin results by sequencing of the rpoB regiona

Isolate Result for:
 Sequencing
MTBDRplus version 2.0 Anyplex GXP
40 S R S Poor sequencing
41b R S R Insertion TTC 432−433
92c R S S Wild type
99d R S R SNP 1862 C>T His>Tyr 445His526Tyr
87e S R S SNP 1184 T>C Leu>Pro 452Leu533Pro
117f S R S SNP 1184 T>C Leu>Pro 452Leu533Pro
a

R, resistant; S, susceptible; WT, wild type.

b

Isolate 41: MTBDRplus version 2.0 mutation in codon 510−519 (rpoB WT 3 missing), no mutation band, GXP probe B not binding.

c

Isolate 92: MTBDRplus version 2.0 S531L mutation, no wild type missing, possibly mixed infection.

d

Isolate 99: MTBDRplus version 2.0 mutation in codon 526−529 (rpoB WT 7 missing) and H526Y mutation, GXP probe D not binding.

e

Isolate 87: Repeat on MTBDRplus version 2.0 (later version) mutation in codon 530−533 (rpoB WT 8 missing), repeat on GXP G4 cartridge probe E not binding.

f

Isolate 117: Repeat on MTBDRplus version 2.0 (later version) mutation in codon 530−533 (rpoB WT 8 missing), repeat on GXP G4 cartridge probe E not binding.