TABLE 3.
Correlation of virulence markers and disease outcomes with the presence of the cag PAI
| Characteristic (no. of isolates) | % of 276 isolates cag+ | % of 101 isolates cag negative |
|---|---|---|
| Virulence markers: | ||
| vacA s1 (277) | 93 | 19 |
| babA2 (268) | 80 | 47 |
| dupA (short/long) (253) | 67 (48/20) | 66 (15/51) |
| iceA2 (208) | 56 | 53 |
| jhp918 (261) | 69 | 69 |
| PZ1 (249) | 68 | 59 |
| PZ2 (177) | 45 | 51 |
| Disease outcomes: | ||
| Gastritis (66) | 77 | 23 |
| Peptic ulcer (41) | 88 | 12 |
| Atrophy/metaplasia/dysplasia (10) | 70 | 30 |
| Gastric cancer (11) | 100 | 0 |
| MALT lymphoma (1) | 0 | 100 |
| Nonulcer dyspepsia (12) | 100 | 0 |
| Other (12)a | 92 | 8 |
| Unknown (224) | 66 | 34 |
a
The category “other” consists of isolates used in mouse and gerbil infection experiments and one isolated from a cat.