Table 2.
IP-10 values in blood and urine of children with or without active TB stratified by HIV infection. Healthy adult donors were included as controls.
| HIV-uninfected children | HIV-infected children | Healthy adult donors | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Culture-confirmed | Highly probable | Probable | Total active TB | Respiratory diseases | Culture-confirmed | Highly probable | Probable | Total active TB | Respiratory diseases | |||
| n | 7 | 7 | 5 | 19 | 61 | — | 10 | 3 | 13 | 18 | 33 | |
|
| ||||||||||||
| Blood IP-10 Median (IQR) |
563.9 (381.9–926.6) |
432.2 (234.4–596.8) |
213.9 (95.9–349.2) |
381.9 (213.9–596.8) |
204.1 (126.4–426.6) |
— | 611.2 (249.7–688.9) |
396.9 (383.6–673.6) |
609.8 (317.6–671.5) |
525.9 (319.7–680.6) |
103.3 (81.9–145.3) |
|
|
| ||||||||||||
| Urine IP-10 Median (IQR) |
4.9e − 006 (0–1.2e − 005) |
3.4e − 006 (0–2.2e − 005) |
0 (0–6.1e − 006) |
3.4e − 006 (0–8.9e − 006) |
9.6e − 007 (0–9.5e − 006) |
— | 1.1e − 005 (0–5.3e − 005) |
2.1e − 006 (0–1.6e − 005) |
7.9e − 006 (0–3.3e − 005) |
1.5e − 006 (0–5.3e − 006) |
6.2e − 007 (0–2.2e − 006) |
|
TB: tuberculosis; IQR: interquartile range; HIV: Human Immunodeficiency Virus.