Table 2.
Association between considered molecular markers groups and overall survival.
| Molecular markers | n | Overall survival Univariate (mean values) |
P | Overall survival Multivariate∗
(hazard ratio) |
P | |
|---|---|---|---|---|---|---|
| CD3/c-kit | Low CD3/low c-kit | 22 | 699.154 | 0.002 | — | NS |
| Low CD3/high c-kit or high CD3/low c-kit | 35 | 500.809 | ||||
| High CD3/high c-kit | 23 | 335.083 | ||||
|
| ||||||
| CD3/VEGF | Low CD3/low VEGF | 20 | 696.583 | 0.006 | — | NS |
| Low CD3/high VEGF or high CD3/low VEGF | 35 | 524.480 | ||||
| High CD3/high VEGF | 25 | 383.500 | ||||
|
| ||||||
| c-kit/VEGF | Low c-kit/low VEGF | 12 | 663.167 | <0.0001 | 6.102 | 0.010 |
| Low c-kit/high VEGF or high c-kit/low VEGF | 26 | 697.143 | ||||
| High c-kit/high VEGF | 42 | 371.462 | ||||
n, number of samples; P, statistical significance; NS, not significant; ∗Cox proportional hazard model: forward stepwise method-likelihood ratio.