Table 1.
Acute toxicity of Artemisia afra aqueous extract in Swiss albino mice (n = 6).
| Dose of A. afra aqueous extract in mg/Kg |
Number of mice per group (n = 6) |
Number of mice dead and percent dead |
Signs of toxicity | ||
|---|---|---|---|---|---|
| 0.00 mg/Kg | Group-1 | M = 3 | 0/3 | 0% | None |
| F = 3 | 0/3 | ||||
|
| |||||
| 1000 mg/Kg | Group-2 | M = 3 | 0/3 | 0% | None |
| F = 3 | 0/3 | ||||
|
| |||||
| 2000 mg/Kg | Group-3 | M = 3 | 0/3 | 0% | None |
| F = 3 | 0/3 | ||||
|
| |||||
| 3000 mg/Kg | Group-4 | M = 3 | 0/3 | 0% | None |
| F = 3 | 0/3 | ||||
|
| |||||
| 4000 mg/Kg | Group-5 | M = 3 | 0/3 | 0% | None |
| F = 3 | 0/3 | ||||
|
| |||||
| 5000 mg/Kg | Group-6 | M = 3 | 0/3 | 0% | Hypoactivity, piloerection |
| F = 3 | 0/3 | ||||
|
| |||||
| 7500 mg/Kg | Group-7 | M = 3 | 1/3 | 16.6% | Hypoactivity, piloerection |
| F = 3 | 0/3 | ||||
|
| |||||
| 10000 mg/Kg | Group-8 | M = 3 | 1/3 | 33.3% | Hyperventilation, hypoactivity, and salivation |
| F = 3 | 1/3 | ||||
|
| |||||
| 12000 mg/Kg | Group-9 | M = 3 | 3/3 | 100% | Convulsion, hyperventilation, hypoactivity, and salivation |
| F = 3 | 3/3 | ||||