Table 2.
Hypoglycemic effect of aqueous and methanolic extracts of Artemisia afra in alloxan induced diabetic mice (n = 5).
| Treatment | Mean change of blood glucose (mg/dL) in hours after treatment (n = 5) | % reduction | |||||
|---|---|---|---|---|---|---|---|
| 0 hr | 1 hr | 2 hr | 3 hr | 4 hr | 5 hr | ||
| Diabetic control | 322 ± 6.3 | 385.5 ± 6.8 | 392.2 ± 5.9 | 382.25 ± 6.1 | 384.7 ± 6.2 | 377.2 ± 6.4 | 0.03% |
| AQ Artemisia 500 | 350.5 ± 3.4 | 349.7 ± 3.7 | 304 ± 3.2 | 311.75 ± 4.0 | 280 ± 3.8∗ | 263.75 ± 3.6∗ | 24% |
| AQ Artemisia 750 | 330.3 ± 2.2 | 274.3 ± 1.8 | 209.3 ± 1.6 | 186 ± 1.8∗ | 152 ± 1.5∗ | 142.3 ± 1.3∗ | 56.9% |
| AQ Artemisia 1000 | 351.7 ± 10.1 | 405.7 ± 9.8 | 402.7 ± 11.2 | 380.7 ± 10.6 | 349.5 ± 10.2 | 324.5 ± 9.9 | 7.6% |
|
| |||||||
| Meth. Artemisia 500 | 293.2 ± 7.7 | 346.7 ± 9.6 | 350 ± 5.2 | 330.5 ± 6.4 | 329 ± 6.1 | 283 ± 7.2 | 3.4% |
| Meth. Artemisia 750 | 354.25 ± 3.8 | 379.5 ± 4.0 | 351.7 ± 5.2 | 303.75 ± 4.6 | 287.75 ± 4.4 | 263.5 ± 3.5 | 25.7% |
| Meth. Artemisia 1000 | 319.5 ± 4.5 | 199.8 ± 5.0 | 204 ± 4.8 | 180.6 ± 2.2∗ | 166.5 ± 1.8∗ | 160.5 ± 2.2∗ | 49.8% |
| Normal control | 110.5 ± 0.22 | 112 ± 0.21 | 114 ± 0.23 | 105 ± 0.28 | 95.25 ± 0.31 | 101 ± 0.25 | 8% |
∗ p < 0.005 as compared to diabetic control.