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Removal of extracellular Ca2+ abolished the increase in [Ca2+]i induced by (a) GSK1016790A (0.1nM-1µM), (b) allyl isothiocyanate (AITC; 1-500µM), and (c) cinnamaldehyde (CA; 1-500µM) in cultured human odontoblast-like cells. The highest doses of each agonist induced a robust increase in [Ca2+]i in the same cells when extracellular Ca2+ was present. n = 3 triplicate measurements.
