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. 2015 Jul 1;114(2):1146–1157. doi: 10.1152/jn.00355.2015

Fig. 3.

Fig. 3.

PigK knockdown phenocopies maco behavior. A: maco+/+ embryos had significantly higher touch response scores than did macott261/tt261 embryos. (n: 10, maco+/+; 12, macott261/tt261). B: PigK morpholino (MO) led to a dose-dependent decrease in touch scores. In contrast, injection of CTL MO had no effect on touch sensitivity. (n = 73, 3.5 ng/nl CTL MO; 76, 0.5 ng/nl PigK MO; 61, 1.5 ng/nl PigK MO; 71, 2.5 ng/nl PigK MO; 72, 3.5 ng/nl PigK MO). For the graphs of A and B, solid horizontal lines designate the median, boxes indicate the 25th–75th percentiles, and whiskers show 90th percentile. C: injection of PigK MO also led to reduction of RB INa amplitudes. D: INa amplitudes were decreased significantly in embryos injected with PigK MO. Data are presented as means ± SE. ***P < 0.001 (n = 3, 3.5 ng/nl MO CTL; 5, 3.5 ng/nl PigK MO).