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. 2015 Jul;10(7):1159–1165. doi: 10.4103/1673-5374.160114

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Copyright: © Neural Regeneration Research

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Effect of topical application of β-NGF neurogenesis in collagen bone substitute-filled defects.

(A–C) Immunohistochemistry for β III-tubulin (A), NF160 (B), and PGP9.5 (C) at bone defect site (× 400; positive immunoreactivity appears brown). (D) Quantitation of β III-tubulin, PGP9.5 and NF160 immunoreactivity in collagen bone substitute-filled defects. All data are expressed as the mean ± SD (n = 6). *P < 0.05, vs. PBS side (paired t-test). β-NGF: β-Nerve growth factor; PGP9.5: protein gene product 9.5; NF160: neurofilament 160; AOD: average optical density; d: days.