Table 2. Effect of melatonin on mean BCVA and CMT.
| Patient no. | Pre-tx BCVA | Pre-tx CMT (μm) | BCVA at 1-month post tx | CMT at 1-month post tx (μm) | Changes in BCVA (letters) | Changes in CMT (μm) |
|---|---|---|---|---|---|---|
| 1 | 20/63 | 640 | 20/20 | 323 | +25 | −317 |
| 2 | 20/32− | 396 | 20/25 | 335 | +6 | −61 |
| 3 | 20/50−2 | 281 | 20/70 | 230 | −13 | −51 |
| 4 | 20/50−2 | 490 | 20/20 | 316 | +22 | −174 |
| 5 | 20/20 | 441 | 20/20 | 227a | 0 | −214 |
| 6 | 20/50 | 270 | 20/32− | 233a | +9 | −37 |
| 7 | 20/40−2 | 399 | 20/20 | 250a | +17 | −149 |
| 8 | 20/32+1 | 389 | 20/32+2 | 202 | +1 | −187 |
| 9 | 20/20−1 | 304 | 20/40 | 295 | −14 | −9 |
| 10 | 20/50+1 | 322 | 20/50−1 | 366 | −2 | +44 |
| 11 | 20/50 | 252 | 20/50+1 | 270 | +1 | +18 |
| 12 | 20/32 | 298 | 20/32−1 | 300 | −1 | +2 |
| 13 | 20/50−2 | 442 | 20/63−1 | 460 | −4 | +18 |
Abbreviations: BCVA, best-corrected visual acuity; CMT, central macular thickness; tx, treatment.
Melatonin-treated patients: 1–8; control group: patients 9–13.
a
Complete resolution of subretinal fluid and/or pigment epithelial detachment (PED).