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. 2015 Aug 19;5:12586. doi: 10.1038/srep12586

Figure 1. Kin28 kinase inhibition reduces nascent transcription and results in polymerase reading through the termination signal.

Figure 1

(A) Schematic depiction of a gene showing the positions of three primers 1, 2, 3, 4, 5, 6, 7 and 5′ primer used for cDNA synthesis following TRO procedure. (B–E) Quantification of RNA levels detected following TRO analysis in Kin28-as mutant in the absence (-NA-PP1) and presence (+NA-PP1) of NA-PP1. The transcript level of 18S was used as the control for normalization of results.