Figure 1.
Effect of RLX on cardiac function index in an isoproterenol (Iso)-induced myocardial fibrosis rat model.
Notes: All experiments were performed in three repetitions. Data are mean ± SEM. **P<0.01 vs control, #P<0.05, ##P<0.01 vs Iso. Iso, 5 mg·kg−1·d−1; low-, middle-, and high-dose RLX at concentrations of 0.2, 2, and 20 μg·kg−1·day−1, respectively.
Abbreviations: RLX, relaxin; LVSP, left-ventricular mean systolic pressure; LVEDP, left-ventricular end diastolic pressure; NS, normal saline; SEM, standard error of the mean; +dp/dtmax, the maximum pressure rise rate of left ventricle; -dp/dtmax, the maximum pressure drop rate of left ventricle.