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. 2015 Jun 30;156(9):3358–3369. doi: 10.1210/en.2014-1874

Figure 7.

Figure 7.

Proposed model for CCL20 action. The LH surge leads to an increased expression of CCL20 in the granulosa and theca cells of the dominant follicle. The presence of CCL20 causes leukocytes from the bloodstream that have CCR6 to migrate into the ovary to aid in the breakdown of the follicular wall leading to oocyte expulsion.