Fig. 3. Knock-down of DKK-1 inhibits cell growth. (A) DKK-1 knock-down in Huh7 cells decreased the amount of secreted DKK-1 after 48 h, determined by ELISA. (B) DKK-1 knock-down inhibited Huh7 cell growth after 48 h, determined by MTT assays. ^*p<0.01. DKK-1, dickkopf-1.