Table E2.
Clinical characteristics of NANA control children and atopic children with STRA used for cultured BECs
| Clinical characteristics | NANA subjects | Children with STRA | P value |
|---|---|---|---|
| No. | 11 | 11 | |
| Sex | 64% M/36% F | 55% M/45% F | 1.00 |
| Age (y) | 7 (2-15) | 11 (9-15) | .11 |
| Family history of atopy | No | Yes | NA |
| Total serum IgE (U/mL) | NA | 374 (121-4610) | NA |
| No. of positive RAST results | NA | 3 (0-6) | NA |
| Cumulative RAST score | NA | 60.4 (0.03-195) | NA |
| Family history of asthma | No | Yes | NA |
| Physician's diagnosis of asthma | No | Yes | NA |
| FEV1 (% predicted) | NA | 79 (36-108) | NA |
| FVC (% predicted) | NA | 80.6 (19-111) | NA |
Values are presented as medians (ranges), except for sex. RASTs include house dust mite, mixed grass pollen, dog, cat, egg white, peanut, mixed tree pollen, Aspergillus fumigatus, Alternaria species, Cladosporium herbarum, and cockroach. The Mann-Whitney U test was used to determine significant differences between the 2 groups. The cumulative RAST score is defined as the total sum of positive RAST scores for each allergen. One hundred percent of children with STRA reported a family history of atopy and asthma and had a physician's diagnosis of asthma. These data were previously reported by Edwards et al.E6
F, Female; FVC, forced vital capacity; M, male; NA, not applicable.