Table 1. Carbohydrate-binding characteristics of LC1q.
| Carbohydrates or carbohydrate residues composing neoglycoproteins | LC1q binding to neoglycoproteins,* RU | IC50,† mM |
|---|---|---|
| GlcNAc | 99.7 | 15 |
| N-acetylmannosamine | ND | 52 |
| GalNAc | 0 | ND |
| Glucose | 0 | >100 |
| Mannose | 0 | >100 |
| Galactose | 0 | >100 |
ND, not determined.
*
Binding of LC1q to each neoglycoprotein was evaluated in terms of resonance units (RU) obtained with surface plasmon resonance analysis
†
The IC50 value of each carbohydrate was determined as the concentration resulting in 50% inhibition of LC1q binding to GlcNAc-BSA