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. Author manuscript; available in PMC: 2015 Aug 20.
Published in final edited form as: Cancer Biol Ther. 2009 Nov 27;8(22):2186–2193. doi: 10.4161/cbt.8.22.10446

Figure 4. Some human colon tumor cells show a sub-population of ALDH-positive cells whose ALDH activity is blocked by the ALDH inhibitor DEAB.

Figure 4

This Aldelfuor assay is employed as a second means (in addition to SP) to identify putative colon cancer stem cells. Three colon cancer cell lines, SW480, SW620, R6, were assayed for the presence of aldehyde dehydrogenase activity. All three lines showed a distinct group of cells shifting to higher fluorescence intensity compared with the control cells with DEAB added. Individual gating was performed according to the profile of DEAB treated samples.