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. 2004 Jun 24;101(27):10183–10188. doi: 10.1073/pnas.0403683101

Fig. 4.

Fig. 4.

Okadaic acid-induced inhibition of GABA-current run-down in pyramidal neurons from human TLE slices. (A) Currents elicited by repetitive applications of GABA to a pyramidal neuron treated with okadaic acid (50 nM, 30 min) before (control), at the end of the run-down protocol (to 81%), and at recovery after 6 min (to 104%). (B) Amplitude of GABA currents elicited by repetitive GABA applications to five pyramidal neurons (patients 2–5; see Table 1), 30 min after okadaic acid treatment, as indicated. Currents were normalized to Imax = -189 ± 23 pA. Superimposed dotted curve is that for pyramidal neurons in Fig. 3B. Arrows are as in Fig. 3.