TABLE 3.

Association between regularity of the activity rhythm and continuous measures of body weight, blood pressure, glucose regulation, and dyslipidemia

		Estimate (SE) p-value on outcome associated with a 1SD increase in IS
Model	Covariates	BMI n=1137	sBP n=497	dBP n=497	HbA1C n=434	HDL n=665
M	Age, Sex	−0.81 (0.15) 1.7e-07	−1.75 (0.89) 5.0e-02	−1.22 (0.51) 1.7e-02	−0.01 (0.02) 6.6e-01	3.03 (0.72) 2.9e-05
N	L + Total Activity	−0.66 (0.16) 5.2e-05	−1.83 (0.94) 5.3e-02	−1.14 (0.54) 3.6e-02	−0.01 (0.02) 6.4e-01	2.45 (0.76) 1.3e-03
O	L + Total Rest	−0.57 (0.17) 7.1e-04	−1.98 (1.00) 4.8e-02	−0.98 (0.57) 8.9e-02	−0.01 (0.02) 5.6e-01	2.27 (0.79) 4e-03
P	L + IV	−0.69 (0.17) 6.2e-05	−2.21 (1.04) 3.4e-02	−1.47 (0.61) 1.6e-02	−0.02 (0.02) 4.3e-01	2.88 (0.80) 3.7e-04
Q	L + kRA	−0.78 (0.15) 5.1e-07	−1.58 (0.90) 7.9e-02	−1.08 (0.52) 3.6e-02	−0.01 (0.02) 6.7e-01	2.92 (0.73) 7.2e-05
R	L + BMI	NA	−1.26 (0.90) 1.6e-01	−0.85 (0.51) 9.8e-02	0.00 (0.02) 9.6e-01	2.03.0 (0.73) 5.7e-03
S	L + CAD + Stroke + PVD	−0.86 (0.16) 1.7e-07	−1.08 (0.97) 2.7e-01	−0.88 (0.57) 1.2e-01	−0.03 (0.02) 2.8e-01	2.45 (0.74) 1.1e-03
T	L + Dementia	−0.86 (0.16) 4.4e-08	−1.68 (0.90) 6.3e-02	−1.12 (0.52) 3.1e-02	−0.00 (0.02) 8.6e-01	2.76 (0.74) 1.9e-04
U	L + Smoking + Alcohol	−0.80 (0.15) 2.9e-07	−1.51 (0.89) 9.0e-02	−1.07 (0.51) 3.2e-02	−0.01 (0.02) 7.5e-01	2.68 (0.72) 2.1e-04

Abbreviations: SE Standard Error. IS interdaily stability, as calculated in the text. IV intradaily variability, as calculated in the text. kRA sleep fragmentation as calculated in the text. Alcohol consumption measured in grams per week. BMI body mass index expressed as kg/m². CAD coronary artery disease. CHF congestive heart failure. sBP systolic blood pressure expressed as millimeters of mercury. dBP diastolic blood pressure expressed as millimeters of mercury. HbA1C the percentage of glycated hemogloblin. HDL high density lipoprotein expressed as mg/dL.