A. Overall cumulative incidence of subsequent mastectomy for brachytherapy vs. WBI
B. Unadjusted and adjusted subsequent mastectomy risks stratified by age and Endocrine status
A. Survival curves depict cumulative incidence of subsequent mastectomy by type of radiation therapy. Shaded areas indicate 95% confidence bands. B. Adjusted hazard ratios are derived from the multivariate model in Table 2, but are calculated using the appropriate interaction term to measure effect sizes of type of radiation therapy in specific subgroups, such as Age<50 and Age≥50. Abbreviations: E (endocrine), WBI (whole breast irradiation)