Table 3.
Medication administered during hospitalization
| Medication | Non-hyponatremia during hospitalization (n = 362) | Hyponatremia during hospitalization (n = 102) | P value |
|---|---|---|---|
| Furosemide | 95.3 % | 95.1 % | 0.931 |
| ACEIs or ARBs | 77.3 % | 64.7 % | 0.01 |
| Sparing diuretics | 24.3 % | 29.4 % | 0.296 |
| Amiodarone | 15.5 % | 22.5 % | 0.093 |
| Potassium supplement | 55.5 % | 53.9 % | 0.774 |
| Positive inotropes | 9.1 % | 31.4 % | <0.001 |
| Organic nitrates | 62.2 % | 54.9 % | 0.186 |
| Digoxin | 25.1 % | 26.5 % | 0.785 |
| Aspirin | 48.1 % | 43.1 % | 0.378 |
| Clopidogrel | 28.7 % | 33.3 % | 0.369 |
| Simvastatin | 46.4 % | 41.2 % | 0.348 |
| Heparin | 9.1 % | 18.6 % | 0.007 |
| Warfarin | 26.5 % | 21.6 % | 0.311 |
| CCBs | 14.4 % | 8.8 % | 0.144 |
| Ubiquinone | 14.7 % | 10.8 % | 0.314 |
| Beta blockers | 13.5 % | 9.8 % | 0.318 |
| Laxative agents | 40.9 % | 38.2 % | 0.630 |
| PPIs | 14.9 % | 22.5 % | 0.069 |
| H2RAs | 22.1 % | 30.4 % | 0.083 |
| Allopurinol | 18.8 % | 20.6 % | 0.683 |
| Benzodiazepine | 21.8 % | 22.5 % | 0.876 |
| Insulin | 7.5 % | 13.7 % | 0.049 |
| Oral anti-diabetics | 6.6 % | 5.9 % | 0.786 |
| Antibiotics | 35.4 % | 71.6 % | <0.001 |
| Beta blockers on discharge | 10.8 % | 12.9 % | 0.555 |
| Length of hospital stay | 8 (5–12) | 11 (8–15) | <0.001 |
| In-hospital death | 7.7 % | 29.1 % | <0.001 |