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. 2015 Aug 20;5:13419. doi: 10.1038/srep13419

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Copyright © 2015, Macmillan Publishers Limited

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Evaluation of collagen deposit in innervated (A,C) and denervated (B,D) lungs by Masson’s trichrome stain. a and b, bleomycin-treated group; c and d, vehicle control group. Following bleomycin, there were more lesions in the intact lung, demonstrated by 1, consolidation of lung parenchyma with loss of alveolar architecture and increased cellularity; 2, subpleural lesions; 3, peri-vascular and peri-bronchial collagen deposits. (E) morphometric analysis shows that collagen deposit was higher in the intact lung. (F) the Ashcroft score was higher in the intact lung. Vx: vagotomy. *P < 0.05, ***P < 0.001, n = 27.