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. 2015 Aug 19;81(18):6253–6267. doi: 10.1128/AEM.01263-15

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Copyright © 2015, van den Broek et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-ShareAlike 3.0 Unported license, which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original author and source are credited.

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FIG 1 — Chromosomal structure and chromosome copy number of the lager brewing strain S. pastorianus CBS1483. The graph represents the ploidy prediction, generated with the Magnolya algorithm (28), of contigs that were de novo assembled by Newbler (454 Life Sciences) and aligned to the reference S. cerevisiae S288C (43) and S. eubayanus CBS12357 (15) genome sequences using NUCMER (MUMmer, version 3.21; www.mummer.sourceforge.net). Blue and red blocks, contributions of the S. cerevisiae (Sc) and S. eubayanus (Seub) subgenomes, respectively, to the S. pastorianus CBS1483 genome organization. The representation of the genomic organization of CBS1483 takes into account the individual chromosome ploidy and the 35 chromosomal structures identified in this study.