Partial Rescue of Adar1 Mutant Embryo Viability and Liver Integrity in Adar1; Ifnar1 Double Mutant
(A and B) Whole embryos and corresponding liver sections of wild-type (A) and Adar1 mutant (B) mice at E11.5.
(C–F) Whole embryos and corresponding liver sections of Adar1; Ifnar1 (C and E) and Adar1; Ifnar1 (D and F) mice at E14.5 (C and D) and E15.5 (E and F).
(G and H) Sectioned whole embryos of Adar1+/+; Ifnar1−/− (G) and Adar1−/−; Ifnar1−/− (H) mice at E15.5. Fetal livers outlined by red boxes.
Scale bars, liver sections (A–F), 25 μm; all others, 1 mm.