Table 1.
Survival of Mouse Embryos with Different Adar1 Genotypes from Crosses between Adar1+/−; Ifnar1−/− (C57Bl6N/129) or Adar1+/−; Mavs−/− (C57Bl6N/J) Parents
| Day | Litters | Embryos | Adar1+/+ | Adar1+/− | Adar1−/− | Exp. Adar1−/− |
|---|---|---|---|---|---|---|
| Parents crossed; Adar1+/−; Ifnar1−/− | ||||||
| E 11.5 | 2 | 14 | 4 | 7 | 3 | 3.50 |
| E 12.5 | 2 | 13 | 6 | 7 | 0 | 3.25 |
| E 13.5 | 4 | 22 | 4 | 14 | 4 | 5.50 |
| E 14.5 | 4 | 28 | 8 | 15 | 5 | 7.00 |
| E 15.5 | 5 | 33 | 16 | 16 | 1 | 8.25 |
| E 16.5 | 2 | 9 | 0 | 6 | 3 | 2.25 |
| E 17.5 | 2 | 10 | 5 | 5 | 0 | 2.50 |
| Total | 129 | 43 | 70 | 16 | ||
| Parents crossed; Adar1+/−; Mavs−/− | ||||||
| E 11.5 | 7 | 59 | 17 | 32 | 10 | 14.75 |
| E 12.5 | 2 | 15 | 4 | 7 | 4 | 3.75 |
| E 13.5 | 2 | 19 | 5 | 10 | 4 | 4.75 |
| E 14.5 | 2 | 11 | 3 | 7 | 1 | 2.75 |
| E 15.5 | 4 | 29 | 8 | 15 | 6 | 7.25 |
| P 0.5 | 7 | 60 | 17 | 35 | 8 | 15.00 |
| Total | 193 | 54 | 106 | 33 | ||