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. 2015 Aug 19;89(18):9338–9347. doi: 10.1128/JVI.01118-15

TABLE 4.

Clinical disease stage scoringa

Time of scoring (mo p.i.) Score for indicated animal
Orally inoculated group
Aerosol-inoculated group
PO-1 PO-2 PO-3 PO-4 PO-5 PO-6 PO-7 PO-8 PO-9 PO-10 A-1 A-2 A-3 A-4 A-5 A-6
3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Termination of study 3 3 3 3 0 2 2 3 3 2
16 0 0 0 0 0 0
19 1 1 1 1 2 3
20 2 1 2 1 2
21 2 2 2 1
22 2 2 2 1
23 2 3 3 2
25 2 3
26 3
a

Deer were given a score of 0 to 4 for clinical disease at each time point when excreta samples were taken. 0, normal behavior; 1, subtle behavioral changes (diurnal rhythms and patterns of sleeping, feeding, and activity are altered); 2, mild but observable neurological deficits, commonly mild ataxia in the hindquarters; 3, early stage, behavioral changes continue, with early signs of deterioration and continued progression of ataxia; 3, late stage, gait abnormalities become pronounced; 4, neurological deficit progression, wide-legged stance, low-hanging head, piloerection, obvious signs of muscle wasting, and increased ataxia. The appetite and ability to eat and drink are intact, with dramatic increases often seen (2 to 3 times normal volumes). †, deer that died during the study.