FIG 2.

rPrP substrates have different inherent amyloidogenicity. (A) Points indicate the average rate of amyloid conversion for each substrate (bovine, feline, and white-tailed deer) upon addition of artificial truncated bank vole rPrP^ThT+. (B) Points indicate the rate of amyloid conversion for each substrate upon the addition of artificial truncated Syrian hamster rPrP^ThT+. Error bars represent the standard errors of the means (SEM) (A and B). (C and D) Each line represents the average ThT fluorescence for 4 replicates for each seed-substrate combination, and the dotted line indicates the threshold for determination of the lag phase.