TABLE 1.
Sources of the prion seeds used in the study experimentsa
Prion type | Species (n) | Prion disease status | Tissue | Inoculum | Inoculation | Sample ID |
---|---|---|---|---|---|---|
CWD | WTD (1) | + | Caudal brain sections | Colorado Department of Wildlife positive deer LA01 | Oral | 104 |
Exper. CWD | WTD (6) | + | Whole brain | CSU CWD-positive deer 700, 800 series | Oral or aerosol | CBP6 |
Negative deer | WTD (1) | − | Caudal brain sections | CSU CWD-negative deer UGA 1/2 | Oral | 123 |
Feline CWD | Feline (2) | + | Multiple brain sections | CSU CWD-positive deer | Intracranial | 4137/4152 |
Negative cat | Feline (1) | − | Obex | CSU CWD-negative deer UGA 1/2 | Oral | 4141 |
FSEb | Feline (1) | + | Medulla | Natural infection | Assumed oral | FSE |
BSE | Bovine (1) | + | Obex | Natural infection | Assumed oral | BSE |
Negative cow | Bovine (1) | − | Brainstem | Not inoculated | Negative bovine | |
Field CWD 1c | WTD | + | Obex | Field isolate | H92 | |
Field CWD 2c | WTD | + | Obex | Field isolate | 98933968 |