Figure 6. Computer simulation of recombination between the YFP and CFP genes.
The recombination of YFP and CFP genes in A549 cells infected with the indicated lentivirus was simulated by computer with a recombination rate of 0.0043 (/base), which showed maximal likelihood estimation. To reproduce the experimental data, 9 parameters were extracted from the experimental data set in Fig. 3 (see Supplementary Fig. S6 and the Methods for details). Red lines were fitted with the e100YPet data. Orange and cyan arrowheads indicate the T203Y and Y66W positions, respectively.