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. 2015 Jul 22;30(9):2222–2233. doi: 10.1093/humrep/dev182

Table I.

Clinical parameters and baseline biomarkers used as covariates in prediction models.

Parameter PPCOS-II
(N = 750)
PPCOS-I
(N = 626)
P-value*
Age 28.9 ± 4.3 28.1 ± 4.0 0.001
Weight (kg) 94.8 ± 26.3 94.3 ± 24.7 0.715
BMI (kg/m2) 35.1 ± 9.3 35.2 ± 8.7 0.849
 <30 245/750 (32.7) 179/625 (28.6) 0.057
 30–34 127/750 (16.9) 135/625 (21.6)
 ≥35 378/750 (50.4) 311/625 (49.8)
Waist circumference (cm) 105.9 ± 20.4 102.5 ± 19.6 0.002
Waist/hip ratio 0.902 ± 0.103 0.864 ± 0.091 <0.001
Hirsutism score 17.0 ± 8.5 14.4 ± 7.9 <0.001
 <8 97/750 (12.9) 121/626 (19.3) <0.001
 8–15 250/750 (33.3) 262/626 (41.9)
 ≥16 403/750 (53.7) 243/626 (38.8)
Race <0.001
 White 590/750 (78.7) 435/623 (69.8)
 Black or African-American 100/750 (13.3) 109/623 (17.5)
 Asian 24/750 (3.2) 17/623 (2.7)
 American Indian or Alaska Native 7/750 (0.9) 72/623 (11.6)
 Native Hawaiian or Pacific Islander 2/750 (0.3) 1/623 (0.2)
 Mixed race 27/750 (3.6)
Ethnic group <0.001
 Not Hispanic or Latino 622/750 (82.9) 462/626 (73.8)
 Hispanic or Latino 128/750 (17.1) 164/626 (26.2)
Length of attempting conception (months) 41.7 ± 37.8 40.4 ± 35.8 0.503
Prior pregnancy 273/750 (36.4) 210/626 (33.6) 0.269
Prior pregnancy loss 174/750 (23.2) 138/626 (22.0) 0.610
Prior live birth 148/750 (19.7) 113/626 (18.1) 0.428
History of smoking 317/750 (42.3) 247/626 (39.5) 0.291
Total testosterone (ng/dl) 55.0 ± 28.8 62.0 ± 28.6 <0.001
Free androgen index 7.8 ± 5.9 9.5 ± 6.7 <0.001
Glucose (mg/dl) 86.0 ± 12.6 89.0 ± 17.4 <0.001
Insulin (µU/ml) 19.3 ± 27.0 23.0 ± 26.6 0.011
Proinsulin (pmol/l) 18.0 ± 14.4 24.9 ± 25.8 <0.001
SHBG (nmol/l) 33.9 ± 23.1 29.7 ± 18.1 <0.001
White blood cells (103/µl) 7.3 ± 1.9 7.3 ± 2.0 0.660

Data are presented as mean ± SD or frequencies (%). There are some missing values.

SHBG, sex hormone-binding globulin.

*Comparison for all patients between PPCOS-I and PPCOS-II studies.