Table 5.
Number of Deaths and Percentage Attributable to Hepatitis C Virus (HCV) Among 9378 NHANES Participants Aged 17–59 Years
| HCV antibody positive |
HCV antibody positive and HCV RNA positive (chronic infection) |
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| Cause of death | Average annual no. of deathsa (95% CI) | Attributable risk percentageb (95% CI) | Average annual no. of deathsa (95% CI) | Attributable risk percentageb (95% CI) |
| All-cause | 33,759 (19,819–57,503) | 52.6 (15.2–73.3) | 31,163 (17,567–55,282) | 57.8 (21.9–77.2) |
| Liver-related | 9390 (2,557–34,482) | 94.9 (84.4–98.3) | 9569 (2,589–35,373) | 96.2 (87.5–98.9) |
| Non–liver-related | 24,369 (14,713–40,362) | 38.3 (−31.6 to 71.3) | 21,595 (12,564–37,116) | 44.1 (−29.9 to 76.1) |
NOTES. CI, confidence interval.
a
Calculated as weighted average annual mortality rates × N, where N was the estimated total population aged 17–59 years who were HCV-antibody positive (3.22 million) and HCV-antibody and HCV-RNA positive (2.46 million).
b
From fully adjusted Cox model: (MRR-1)/MRR ×100.