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Percentage of a simulated population (n = 1000) with average day 14 RBV-MP concentrations above the determined thresholds for SVR (4.4 pmol/106 cells) and anaemia (6.1 pmol/106 cells)
| Dose (mg) | Cave (pmol/106 cells) | Percentage above SVR threshold (4.4 pmol/106 cells) | Percentage above anaemia threshold (6.1 pmol/106 cells) |
|---|---|---|---|
| 600 | 4.27 | 44.4 | 2.3 |
| 800 | 5.69 | 85.6 | 37.0 |
| 1000 | 7.12 | 96.3 | 74.8 |
| 400/600 | 7.13 | 96.7 | 75.6 |
| 1200 | 8.54 | 98.8 | 90.9 |
| 600/600 | 8.55 | 99.0 | 91.5 |
| 1400 | 9.96 | 99.5 | 96.5 |
| 600/800 | 9.98 | 99.6 | 96.9 |
