Table 6.
Receptor | Tissue | log(Hemangioblastoma) |
log(RCC) | P value (t-test) | P value (Wilcoxon's rank sum test) | ||
Mean | SD | ||||||
pVEGFR2 | Endothelium | 11.268 | 0.498 | 11.752 | 0.378 | 0.001 | 0.003 |
VEGFR total | Endothelium | 12.977 | 0.478 | 13.081 | 0.859 | 0.639 | 0.192 |
pPDGFR | Endothelium | 10.952 | 0.654 | 10.805 | 0.839 | 0.539 | 0.82 |
PDGFR total | Endothelium | 13.078 | 0.659 | 12.842 | 0.851 | 0.333 | 0.947 |
VEGFR ratio | Endothelium | 0.206 | 0.122 | 0.372 | 0.431 | 0.105 | 0.043 |
PDGFR ratio | Endothelium | 0.145 | 0.067 | 0.157 | 0.077 | 0.608 | 0.602 |
Tie2 | Endothelium | 12.654 | 0.455 | 12.63 | 0.817 | 0.909 | 0.883 |
Tie2 | Whole tumor | 11.598 | 0.321 | 11.614 | 0.303 | 0.866 | 0.947 |
FGFR3 | Endothelium | 12.265 | 0.448 | 12.29 | 0.961 | 0.914 | 0.495 |
FGFR3 | Whole tumor | 11.439 | 0.224 | 11.338 | 0.106 | 0.0075 | 0.174 |
pFRS2 | Endothelium | 12.495 | 0.492 | 11.91 | 0.989 | 0.023 | 0.059 |
pFRS2 | Whole tumor | 11.452 | 0.258 | 11.258 | 0.089 | 0.003 | 0.003 |
RCC, renal cell carcinoma; SD, standard deviation; pVEGFR, phosphorylated vascular endothelial growth factor receptor; VEGFR, vascular endothelial growth factor receptor; pPDGFR, phosphorylated platelet-derived growth factor receptor; PDGFR, platelet-derived growth factor receptor; FGFR3, fibroblast growth factor receptor-3; pFRS2, phosphorylated fibroblast growth factor receptor substrate-2.