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CaSR-mediated [Ca2+]i elevation in STC1 cells is TRPA1-dependent. Induction of [Ca2+]i increase by CaSR agonist NPS 568 (20 µM) was inhibited by TRPA1 antagonists HC030031 (50 µM) or A967079 (50 µM) as well as CaSR antagonist NPS 2143 (30 µM). Results are representative of 3 independent experiments.
