Figure 2.

Resistance of ABCB1-positive SP cells to paclitaxel. Fluorescence-activated cell sorting-purified SP and NSP fractions of the ovarian cancer cell lines A2780V and IGROV1 were treated with increasing concentrations of paclitaxel and subsequently subjected to the metabolic colorimetric MTT assay. Nontreatment controls were included and used for calculation of the degree of specific inhibition of cell viability. ∗, p < .05; ∗∗, p < .01. Abbreviations: NSP, non-side population; SP, side population.