Table 3.
Survival Analysis of Neurological Signs in Human T-Cell Lymphotropic Virus Type 1 (HTLV-1)–Infected Subjects Without HTLV-1–Associated Myelopathy/Tropical Spastic Paraparesis
| Sign | Initial Population Without Respective Symptom, no./No. (%) | Sample With Follow-up, no./No. (%) | Proportion of Failures, no./No. (%) | Median Person-time Observation, y, (Max-Min) | Incidence Rate/1000 Person-years (95% CI) |
|---|---|---|---|---|---|
| Neurological exam | |||||
| Arm hyperreflexia | 194/236 (82.2) | 135/194 (69.6) | 20/135 (14.8) | 2 (1–7) | 45.0 (30–72) |
| Leg hyperreflexia | 198/244 (81.1) | 148/198 (74.7) | 34/148 (22.9) | 2 (1–7) | 75.8 (54–106) |
| Leg weakness | 240/240 (100) | 180/240 (75.0) | 34/180 (18.8) | 3 (1–7) | 52.5 (37–73) |
| Babinski sign | 243/243 (100) | 181/243 (74.5) | 25/181 (13.8) | 3 (1–7) | 36.6 (25–55) |
| Neurological scales | |||||
| EDSS | … | 185/251 (73.7) | 78/185 (42.1) | 2 (1–7) | 133.7 (107–167) |
| Delay in 10 s in walking 8 m | … | 184/237 (77.6) | 9/184 (4.8) | 4 (1–7) | 12.1 (6–23) |
Abbreviations: CI, confidence interval; EDSS, Expanded Disability Status Scale.