Table 1.
Comparisons of arcuate fasciculus diffusion metrics in typically developing (TD) control and deletion carriers groups are shown. Slope values were computed from the model across both groups. Group comparison marginal means are reported which factor out age, site, and hemisphere. Developmental trajectory and hemispheric asymmetry values are for both groups. Bold p-values are < 0.05.
| Group comparison |
Developmental trajectory |
Hemispheric asymmetry |
|||
|---|---|---|---|---|---|
| TD mean (±SE) |
Deletion mean (±SE) |
p-Value | Slope vs age (years) (p-value) |
Left–right (p-value) |
|
| Mean diffusivity 10−4 mm2/s |
7.34 (±0.031) |
7.47 (±0.034) |
<0.005 | −0.064 (<0.0001) |
−0.038 (<0.05) |
| Fractional anisotropy | 0.535 (±0.0039) |
0.529 (±0.0042) |
0.3 | 0.0034 (<0.002) |
0.019 (<0.001) |
| Axial diffusivity 10−4 mm2/s |
12.1 (±0.048) |
12.2 (±0.051) |
0.052 | −0.047 (<0.001) |
0.16 (<0.001) |
| Radial diffusivity 10−4 mm2/s |
4.94 (±0.040) |
5.08 (±0.043) |
<0.02 | −0.062 (<0.001) |
−0.12 (<0.001) |