Table 3.
Comparisons of auditory radiation diffusion metrics in typically developing (TD) control and deletion carrier groups are shown. Slope values were computed from the model across both groups. Group comparison marginal means are reported which factor out age, site, and hemisphere. Developmental trajectory slopes are for both groups. Bold p-values are < 0.05.
| Group comparison |
Developmental trajectory |
|||
|---|---|---|---|---|
| TD | Deletion | p-Value | Slope vs age (years) (p-value) |
|
| Mean diffusivity 10−4 mm2/s |
7.51 (±0.034) |
7.62 (±0.038) |
<0.05 | −0.045 (<0.0001) |
| Fractional anisotropy | 0.481 (±0.0056) |
0.492 (±0.0063) |
0.25 | 0.0051 (<0.002) |
| Generalized FA | 0.484 (±0.0047) |
0.494 (±0.0052) | 0.14 | 0.0037 (<0.01) |
| Axial diffusivity 10−4 mm2/s |
11.8 (±0.062) |
12.1 (±0.069) |
<0.002 | −0.01 (0.5) |
| Radial diffusivity 10−4 mm2/s |
5.38 (±0.051) |
5.40 (±0.057) |
0.8 | −0.064 (<0.0001) |