Table 1. Complement regulators.

Characteristic	Regulators
Soluble regulators
Specific	AP: factor H, FHL1, properdin
Control only AP, CP, or LP	CP, AP, LP: carboxypeptidase N
Act exclusively on either C3 or C4	CP, LP: C4 BP, C1 inhibitor
	CP: C1q
	TP: CFHR1, clusterin, vitronectin
Membrane-bound regulators
Control 3 major pathways	CR1, CR2, CR3, CR4, MCP, DAF
Inactivate both C3 and C4

AP, alternative pathway; CP, classical pathway; LP, lectin pathway; FHL1, factor H like protein 1; C4 BP, C4-binding protein; TP, terminal pathway; CFHR1, complement factor H-related protein 1; CR, complement receptor; MCP, membrane cofactor protein; DAF, decay-accelerating factor.